The State of HealthTech in 2025: R2G Releases Global “HealthTech Startup Nation Report” Based on 8,600+ Companies

The HealthTech industry is evolving rapidly. To provide a clear picture of where the industry stands today and where it’s heading, Research2Guidance (R2G) has released a new report: The HealthTech Startup Nation Report – 2025.

Based on exclusive data from R2GConnect, this report offers one of the most comprehensive analyses of the global HealthTech startup ecosystem to date. Drawing on insights from 8,600+ HealthTech companies across 108 countries, the report benchmarks startup performance, funding, team structures, business models, and more.

Download the full report here

A Global Snapshot of the HealthTech Startup Landscape

The HealthTech Startup Nation Report is the result of R2G’s continuous industry monitoring and data collection. It reflects a rich, diverse landscape of startups across Europe, North America, and the rest of the world, giving equal weight to each region for a balanced, global perspective.

The report answers some of the most pressing questions faced by startups, investors, and stakeholders alike:

• How do HealthTech startups perform in different regions and sectors?
• Which therapeutic areas are attracting the most innovation and investment?
• What business models lead to higher revenue and funding success?
• How much does prior startup experience influence investor confidence?
• What roles do certifications and regulatory pathways play in shaping a company’s trajectory?
• What types of partnerships are HealthTech startups seeking most?

Whether you’re a founder looking to benchmark your business, an investor seeking high-potential startups, or a healthcare organization scouting innovation partners, this report offers the strategic intelligence you need.

Benchmarking Your Startup Against the Global Market

With over a decade of expertise in digital health, R2G understands that context is everything. The HealthTech Startup Nation Report helps founders understand where their company stands relative to the broader ecosystem, providing:

• Team Structure Analysis: Explore how startup teams are built around key capabilities like technology, medical expertise, and business development.
• Business Model Comparison: Discover which models – B2B, B2C, or hybrid are showing the most promise in terms of revenue growth and sustainability.
• Therapeutic Focus Areas: Get insights into which clinical domains (e.g., mental health, chronic disease management, remote monitoring) are receiving the most startup attention and achieving the strongest business results.

This benchmark is not just descriptive – it’s actionable. It allows companies to identify gaps and opportunities in their current strategies and pivot toward more successful approaches.

What Makes a HealthTech Startup Successful in 2025?

The report dives deep into the factors that contribute to a startup’s success or struggle in today’s competitive HealthTech space. A few highlights include:

• Certification as a Differentiator: Regulatory certifications like CE, FDA, and HIPAA can have a significant impact on both funding potential and go-to-market strategy.
• Founding Experience: Teams with previous entrepreneurial experience tend to attract more investor attention and form stronger partnerships.
• Revenue vs. Funding: While funding is often considered the key metric, the report reveals that revenue generation is a more reliable indicator of startup maturity and long-term sustainability.
• Partnership Needs: Startups are increasingly seeking collaborations with hospitals, accelerators, service providers, and investors. These partnerships are critical for scaling up solutions and entering new markets.

Why This Report Matters for the Industry

HealthTech is no longer a niche, it’s an essential pillar of the global healthcare system. As the space grows, it’s more important than ever to understand its dynamics and prepare for its future. The HealthTech Startup Nation Report – 2025 gives the industry an evidence-based map to navigate growth and innovation.

This report is especially valuable for:

• Startup Founders looking to benchmark and fine-tune their strategy
• Investors seeking data-driven insights to guide portfolio decisions
• Healthcare Providers aiming to identify and engage with innovative partners
• Accelerators and Incubators supporting early-stage ventures
• Policy Makers and Analysts interested in shaping supportive HealthTech ecosystems

Join the R2GConnect Global HealthTech Community

In addition to publishing reports like this, R2G operates R2GConnect, a dynamic matchmaking and intelligence platform that connects HealthTech startups with industry stakeholders around the world.

Join our community to discover:

• Potential business partners
• Active investors and VCs
• Hospital systems open to collaboration
• Global accelerator programs
• Trusted service providers

Whether you’re building a solution from scratch or scaling your innovation globally, R2GConnect is your gateway to growth.

Find more information here

About Research2Guidance
R2G has been a trusted advisor and data partner to the global digital health industry since 2010. Our mission is to support startups, corporates, and investors with strategic insights and industry know-how. We help digital health businesses thrive across every therapeutic area, business model, and global region.

We’re always happy to connect, share what we’ve learned, and help you navigate the exciting world of HealthTech. Let’s shape the future of healthcare together.